NFL Schedule This Week: Key Fixtures and Betting Odds

The 2026 NFL schedule has been released, with odds available for every game.

Season Opener and International Games

The Seattle Seahawks will open the season on Wednesday, Sept. 9, hosting the New England Patriots in a Super Bowl LX rematch. The Seahawks are 4.5-point favourites.

There is an ever increasing slate of international games — nine in total this season — including the first-ever NFL game played in Australia between the San Francisco 49ers and Los Angeles Rams. The game is on Thursday, Sept. 10 at 8:35 p.m. ET and the Rams are 2.5-point favourites.

Thanksgiving and Thanksgiving Eve Matchups

The Thanksgiving games are headlined by Josh Allen’s Buffalo Bills hosting Patrick Mahomes’ Kansas City Chiefs as 2.5-point favourites on Thursday night. There is also the NFL’s first-ever Thanksgiving Eve game between the Green Bay Packers and Los Angeles Rams.

Week 1 Games and Odds

Here are some of the odds at sportsbooks for NFL games this season (spread is the first number in parentheses and game total is the second):

  • New England Patriots at Seattle Seahawks (-4.5, 45.5)
  • San Francisco 49ers vs. Los Angeles Rams (-2.5, 49.5) in Melbourne, Australia
  • Chicago Bears (-2.5, 45.5) at Carolina Panthers
  • Cleveland Browns at Jacksonville Jaguars (-7.5, 39.5)
  • Buffalo Bills (-1.5, 44.5) at Houston Texans
  • Baltimore Ravens (-3.5, 49.5) at Indianapolis Colts
  • Atlanta Falcons at Pittsburgh Steelers (-2.5, 41.5)
  • New York Jets at Tennessee Titans (-2.5, 38.5)
  • New Orleans Saints at Detroit Lions (-7.5, 48.5)
  • Tampa Bay Buccaneers at Cincinnati Bengals (-3.5, 51.5)
  • Miami Dolphins at Las Vegas Raiders (-3, 40.5)
  • Washington Commanders at Philadelphia Eagles (-4.5, 47.5)
  • Green Bay Packers (-1.5, 46.5) at Minnesota Vikings
  • Arizona Cardinals at Los Angeles Chargers (-9.5, 46.5)
  • Dallas Cowboys (-2.5, 47.5) at New York Giants
  • Denver Broncos at Kansas City Chiefs (-2.5, 42.5)

Later Season Games

Other games include Packers (-6.5, 42.5) at NY Jets, Panthers at Falcons (-1.5, 43.5) and Patriots (-4.5, 43.5) at Steelers.

Additional matchups feature Browns at Buccaneers (-5.5, 42.5), Raiders at LA Chargers (-8.5, 42.5), Jaguars at Broncos (-2.5, 43.5), and Seahawks (-10, 44.5) at Cardinals.

The schedule also includes 49ers (-10.5, 46.5) at Dolphins, Commanders at Cowboys (-4.5, 51.5), Falcons at Packers (-7.5, 46.5), and Seahawks (-3.5, 46.5) at Commanders.

More games include Patriots at Jaguars (-1.5, 45.5), Bengals (-1.5, 47.5) at Steelers, Panthers (-1.5, 39.5) at Browns, and LA Chargers at Bills (-2.5, 48.5).

Vikings at Buccaneers (-1.5, 44.5), Cardinals at 49ers (-11.5, 46.5), Steelers (-2.5, 40.5) at Browns, and Colts at Commanders (-1.5, 48.5) (London) are also on the schedule.

Other matchups are Cardinals at NY Giants (-7, 45.5), Jaguars at Bengals (-2.5, 51.5), Packers (-1.5, 47.5) at Buccaneers, and Dolphins at Vikings (-7.5, 43.5).

LA Chargers at Seahawks (-3, 45.5), Buccaneers at Cowboys (-3.5, 52.5), Eagles (-2.5, 44.5) at Jaguars (London), and Raiders at Patriots (-8.5, 44.5) are also scheduled.

The schedule rounds out with Bengals (-5.5, 49.5) at Dolphins, and NY Giants at Commanders (-2.5, 48.5).

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